Sampliner R E
Department of Internal Medicine, University of Arizona College of Medicine, Tucson.
Gastroenterologist. 1994 Sep;2(3):184-7.
Barrett's esophagus is a premalignant condition, the recognition of which is increasing because of widespread utilization of upper endoscopy. Awareness and identification of the squamocolumnar junction are key to endoscopic recognition of Barrett's esophagus. Biopsy is essential to document Barrett's esophagus and to detect dysplasia. Specific mucosal abnormalities need to be targeted. In addition, systematic biopsies need to be taken for dysplasia/carcinoma surveillance. Experimental endoscopic application of energy to Barrett's esophagus offers the potential for elimination of this lesion. Endoscopic recognition and diagnosis remain the key to clinical management of Barrett's esophagus.
巴雷特食管是一种癌前病变,由于上消化道内镜检查的广泛应用,其识别率正在上升。认识和识别鳞柱状上皮交界处是内镜识别巴雷特食管的关键。活检对于确诊巴雷特食管和检测发育异常至关重要。需要针对特定的黏膜异常进行活检。此外,还需要进行系统性活检以监测发育异常/癌变情况。内镜下对巴雷特食管进行能量实验性应用为消除该病变提供了可能。内镜识别和诊断仍然是巴雷特食管临床管理的关键。