Gregory R L
Indiana University, School of Dentistry, Indianapolis.
Compendium. 1994 Oct;15(10):1282, 1284, 1286 passim; quiz 1294.
Dental caries, caused by the etiologic agent Streptococcus mutans, is considered the most common human infectious disease. Development of a vaccine has been under investigation for more than 25 years. Possible approaches include immunizing patients using an oral vaccine containing components of the causative bacterium and by intramuscular injection. Although both approaches have proved promising, several considerations have delayed further development of a vaccine. This article reviews the scientific results and status of the various vaccines.
由变形链球菌这种病原体引起的龋齿被认为是最常见的人类传染病。疫苗的研发已经进行了25年多。可能的方法包括使用含有致病细菌成分的口服疫苗对患者进行免疫以及通过肌肉注射。尽管这两种方法都已证明有前景，但一些因素阻碍了疫苗的进一步研发。本文综述了各种疫苗的科学成果和现状。
