Oxygen radicals and calcium ion flux: role in reperfusion injury following AMI.

Occlusion of coronary vessels is now frequently treated by reperfusion using thrombolytics, angioplasty, or coronary artery bypass surgery. On reperfusion, however, acutely ischemic cells may be damaged by the action of oxygen radicals on cell membranes, and by calcium ion flux. By understanding the mechanisms behind reperfusion injury, the critical care nurse can assess and plan for actual and potential patient care problems.