Chen Y H, Chen M X, Alessi D R, Campbell D G, Shanahan C, Cohen P, Cohen P T
Department of Biochemistry, University of Dundee, Scotland, UK.
FEBS Lett. 1994 Dec 12;356(1):51-5. doi: 10.1016/0014-5793(94)01231-8.
The structures of the M110 and M21 regulatory subunits of protein phosphatase-1M, the major enzyme which dephosphorylates myosin in smooth muscle, have been deduced from cloned cDNAs. The N-terminus of the M110 subunit from rat aorta contains seven ankyrin repeats, while the C-terminus of the M21 subunit from chicken gizzard contains a leucine zipper motif. The M110 subunit is expressed in two different forms which differ in their C-terminal sequences. One of these is highly homologous to the whole of the M21 subunit.
