Xq22近端布鲁顿酪氨酸激酶和α-半乳糖苷酶A基因座区域的物理图谱构建。
Physical mapping in the region of the Bruton's tyrosine kinase and alpha-galactosidase A gene loci in proximal Xq22.
作者信息
Sweatman A K, Bradley L A, Lovering R C, O'Reilly M A, Levinsky R J, Kinnon C
机构信息
Molecular Immunology Unit, University of London, UK.
出版信息
Hum Genet. 1994 Dec;94(6):624-8. doi: 10.1007/BF00206955.
PMID:7989038
Abstract
We have produced physical maps of the proximal part of Xq22, containing the Bruton's tyrosine kinase (BTK) and alpha-galactosidase A (GLA) gene loci, using long range physical mapping techniques and yeast artificial chromosomes (YACs). These maps reveal five previously unidentified CpG islands which could indicate the presence of other genes in this region.
摘要
我们利用长程物理图谱技术和酵母人工染色体（YAC）构建了Xq22近端部分的物理图谱，该区域包含布鲁顿酪氨酸激酶（BTK）和α-半乳糖苷酶A（GLA）基因座。这些图谱揭示了五个先前未被识别的CpG岛，这可能表明该区域存在其他基因。
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