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宫内人工授精、宫颈妊娠及甲氨蝶呤成功治疗

Intra-uterine insemination, cervical pregnancy and successful treatment with methotrexate.

作者信息

Balasch J, Peñarrubia J, Ballescá J L, Creus M, Casamitjana R, Vanrell J A

机构信息

Department of Obstetrics and Gynaecology, University of Barcelona, Hospital Clínic i Provincial, Spain.

出版信息

Hum Reprod. 1994 Aug;9(8):1580-3. doi: 10.1093/oxfordjournals.humrep.a138753.

DOI:10.1093/oxfordjournals.humrep.a138753
PMID:7989526
Abstract

Cervical pregnancy is rare but one of the most dangerous of all pregnancy complications. The aetiology of cervical implantation is unclear and because of the fear of profuse haemorrhage abdominal hysterectomy has been historically considered the standard therapy. We report here an unusual case of an infertile woman with cervical ectopic pregnancy after ovulation induction with gonadotrophins and intrauterine insemination. The patient was successfully treated with parenteral methotrexate without significant morbidity. It is concluded that chemotherapy should be initially considered in most cervical pregnancies either as the sole form of treatment or to improve the chances of success in alternative conservative measures.

摘要

宫颈妊娠虽罕见,但却是所有妊娠并发症中最危险的之一。宫颈着床的病因尚不清楚,由于担心大出血,传统上一直将腹式子宫切除术视为标准治疗方法。我们在此报告一例不寻常的病例,一名不孕妇女在使用促性腺激素诱导排卵并进行宫内授精后发生宫颈异位妊娠。该患者经胃肠外甲氨蝶呤成功治疗,未出现明显并发症。结论是,在大多数宫颈妊娠中,应首先考虑化疗,要么作为唯一的治疗方式,要么提高替代保守措施的成功率。

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