Becker D, Hershkowitz M, Maidler N, Rabinowitz M, Floru S
Department of Psychiatry, Chaim Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel.
J Nerv Ment Dis. 1994 Dec;182(12):701-3. doi: 10.1097/00005053-199412000-00004.
This study investigated the correlation between the degree and quality of cognitive impairment and the presence and degree of severity of psychopathology. Sixty-four demented outpatients were rated for cognition by the Mental Status Questionnaire and for psychopathology by the BEHAVE-AD Reisberg questionnaire. A statistical analysis of the correlations between the cognitive and psychopathological parameters was performed. The study indicated a high rate of psychopathology (as high as 83% of the patients). No significant correlation was found between the cognitive grading score and the presence of psychopathology, except in the space of declined spatial orientation and the occurrence of hallucinations. Psychopathology is a common phenomenon occurring in the course of dementia in the form of Alzheimer's disease or multi-infarct dementia. There is a certain increase in the degree of psychopathology that correlated with cognitive impairment. The high correlation between impaired spatial orientation and the presence of hallucinations seems to point to a common neuropathological substrate.
本研究调查了认知障碍的程度和质量与精神病理学的存在及严重程度之间的相关性。通过精神状态问卷对64名痴呆门诊患者的认知进行评分，并通过BEHAVE-AD Reisberg问卷对精神病理学进行评分。对认知和精神病理学参数之间的相关性进行了统计分析。研究表明精神病理学发生率很高（高达83%的患者）。除了在空间定向下降和幻觉发生方面，未发现认知分级评分与精神病理学的存在之间存在显著相关性。精神病理学是以阿尔茨海默病或多发梗死性痴呆形式出现的痴呆过程中常见的现象。精神病理学程度有一定增加，这与认知障碍相关。空间定向受损与幻觉存在之间的高度相关性似乎指向一个共同的神经病理学基础。
