Hughes A D, Wijetunge S, Parkinson N A
Department of Clinical Pharmacology, St. Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, London, UK.
J Hum Hypertens. 1994 Aug;8(8):615-8.
Small arteries less than 500 microns make a significant contribution to peripheral vascular resistance. Single vascular smooth muscle cells were isolated from human omental resistance arteries by enzymatic dispersion. The method yielded relaxed vascular smooth muscle cells approximately 120 microns long and 7 microns wide. The cells were studied using whole cell voltage clamp techniques and a number of passive and active membrane properties were described.
直径小于500微米的小动脉对周围血管阻力有显著贡献。通过酶分散法从人网膜阻力动脉中分离出单个血管平滑肌细胞。该方法得到了长度约120微米、宽度约7微米的松弛血管平滑肌细胞。使用全细胞膜片钳技术对这些细胞进行了研究，并描述了一些被动和主动膜特性。
