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[一例右心室散发性黏液瘤切除病例:DNA 流式细胞术辅助诊断]

[A resected case of sporadic myxoma of the right ventricle: the diagnosis was supported with DNA flow cytometry].

作者信息

Ueno Y, Yanagihara K, Toba T, Isobe J, Inoue R, Nishio I, Yamaguchi M, Uemura H, Ito M

机构信息

Department of Surgery, Gifu National Hospital, Japan.

出版信息

Kyobu Geka. 1994 Nov;47(12):1020-2.

PMID:7990280
Abstract

We report a rare case of a 16-year-old male who had myxoma originating from septal band of the right ventricle. His ECG anomaly was found incidentally upon a physical examination. Subsequently, echocardiography and angiocardiography demonstrated a tumor occupying the right ventricular outflow tract and protruding into the main pulmonary artery in systolic phase. He was operated upon using extracorporeal circulation. By right ventriculotomy the tumor was resected together with septal tissue 5 mm around the stalk, which branched into the myocardium. The defect was closed using mattress sutures with Dacron felt strips. We also analyzed the DNA content of the tumor. The DNA flow cytometry yielded a single cell population with diploid DNA content. This result showed that the tumor is sporadic form of cardiac myxoma. His postoperative course was uneventful. Thirty months after the surgery, patient has no sign of recurrence. The DNA flow cytometry is helpful for detecting clinical behavior of the cardiac myxoma, because microscopic examination can not readily distinguish sporadic myxoma from so-called complex myxoma.

摘要

我们报告了一例罕见病例,一名16岁男性患有起源于右心室间隔带的黏液瘤。他的心电图异常是在体检时偶然发现的。随后,超声心动图和心血管造影显示,在收缩期有一个肿瘤占据右心室流出道并突入主肺动脉。他接受了体外循环手术。通过右心室切开术,将肿瘤连同其蒂周围5毫米的间隔组织一起切除,该蒂组织分支进入心肌。使用带涤纶毡条的褥式缝线关闭缺损。我们还分析了肿瘤的DNA含量。DNA流式细胞术产生了一个具有二倍体DNA含量的单细胞群体。这一结果表明该肿瘤是心脏黏液瘤的散发性形式。他的术后过程平稳。手术后30个月,患者没有复发迹象。DNA流式细胞术有助于检测心脏黏液瘤的临床行为,因为显微镜检查不易区分散发性黏液瘤和所谓的复杂性黏液瘤。

相似文献

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[Myxoma of the right ventricle. Apropos of 2 cases].
Arch Mal Coeur Vaiss. 1986 Feb;79(2):244-8.
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[Successful excision of right ventricular myxoma].
Nihon Kyobu Geka Gakkai Zasshi. 1991 Mar;39(3):341-4.

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