Paleev N R, Leskin G S, Turanova Z R, Baklykova S N, Chereĭskaia N K
Klin Med (Mosk). 1994;72(3):24-6.
25 males and 5 females suffering from chronic obstructive bronchitis (COB) underwent transcutaneous diaphragmatic electrostimulation (TDE). As shown by central intrapulmonary hemodynamics, those patients who had no circulatory decompensation benefited from TDE. There was a decrease in the pulmonary hypertension, intensification of general hemodynamics, reduced tonicity of the pulmonary arteriolar bed, improvement of right ventricular function. In circulatory decompensation TDE may cause deterioration of right ventricular function, enhancement of circulation decompensation against unchanged pulmonary hypertension and pulmonary-arteriolar tonicity. The changes in pulmonary artery pressure, total pulmonary vascular resistance, pulmonary-arteriolar elasticity observed after a single TDE session may prompt the validity of further COB treatment according to the above regimen.
25名男性和5名患有慢性阻塞性支气管炎(COB)的女性接受了经皮膈神经电刺激(TDE)治疗。如中心肺内血流动力学所示,那些没有循环失代偿的患者从TDE治疗中获益。肺动脉高压降低,全身血流动力学增强,肺小动脉床张力降低,右心室功能改善。在循环失代偿时,TDE可能导致右心室功能恶化,在肺动脉高压和肺小动脉张力不变的情况下循环失代偿加剧。单次TDE治疗后观察到的肺动脉压、总肺血管阻力、肺小动脉弹性的变化可能提示按照上述方案进一步治疗COB的有效性。