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马齿苋和千日菊水醇提取物对尿钠和钾排泄的影响。

Effects of hydroalcoholic extracts of Portulaca pilosa and Achyrocline satureioides on urinary sodium and potassium excretion.

作者信息

Rocha M J, Fulgencio S F, Rabetti A C, Nicolau M, Poli A, Simões C M, Ribeiro-do-Valle R M

机构信息

Departamentos de Fisiologia, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

出版信息

J Ethnopharmacol. 1994 Jul 22;43(3):179-83. doi: 10.1016/0378-8741(94)90040-x.

Abstract

Porulaca pilosa has been used in Brazil as a traditional remedy to cause diuresis, antipyresis and analgesia. Achyrocline satureioides has been used in folk medicine as antiinflammatory, hypoglycemic, sedative and to treat gastrointestinal disorders such as diarrhea and dysentery suggesting that it may affect salt and water reabsorption by the gastrointestinal tract. In the current study, hydroalcoholic extracts of both plants were investigated in order to examine their renal effects. The results support the claim that extracts of P. pilosa present renal effects but not the popular belief that it affects diuresis. It has also been provided that, in rats, it causes an increase in K excretion without a concomitant change in water diuresis or Na excretion. Our findings also support the popular belief that A. satureioides does not apparently have renal effects and it might change renal ion transport based on observations that it affects gastrointestinal reabsorption.

摘要

毛马齿苋在巴西一直被用作传统药物,具有利尿、解热和镇痛作用。千日菊在民间医学中被用作抗炎、降血糖、镇静药物,并用于治疗胃肠道疾病,如腹泻和痢疾,这表明它可能会影响胃肠道对盐和水的重吸收。在本研究中,对这两种植物的水醇提取物进行了研究,以考察它们对肾脏的作用。结果支持了毛马齿苋提取物具有肾脏作用这一说法,但并不支持它影响利尿的普遍观点。研究还表明,在大鼠中,它会导致钾排泄增加,而水利尿或钠排泄没有相应变化。我们的研究结果也支持了普遍观点,即千日菊显然没有肾脏作用,并且基于它影响胃肠道重吸收的观察结果,它可能会改变肾脏离子转运。

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