Brown P, Rothwell J C, Thompson P D, Marsden C D
MRC Human Movement and Balance Unit, National Hospital for Neurology and Neurosurgery, London, U.K.
Mov Disord. 1994 Sep;9(5):571-6. doi: 10.1002/mds.870090511.
The clinical and electrophysiological characteristics of eight patients with propriospinal myoclonus are described. Myoclonus developed within days or weeks of cervical trauma in half the patients. Seven cases had axial flexion jerks, and one axial extension jerks. Myoclonic EMG activity consisted of repetitive bursts with a frequency of 1-7 Hz. The jerks in three of the cases were comprised of alternating and rhythmic bursts of EMG activity in rectus abdominis and the paraspinal muscles. From these new observations, it is proposed that cervical trauma can lead to the partial release of a spinal pattern generator. The latter is capable of recruiting muscles through long propriospinal pathways into complex rhythmic activity.
本文描述了8例脊髓性肌阵挛患者的临床和电生理特征。半数患者在颈椎外伤后数天或数周内出现肌阵挛。7例出现轴向屈曲抽搐，1例出现轴向伸展抽搐。肌阵挛性肌电图活动由频率为1-7Hz的重复爆发组成。其中3例患者的抽搐由腹直肌和椎旁肌中肌电图活动的交替性和节律性爆发组成。基于这些新观察结果，有人提出颈椎外伤可导致脊髓模式发生器的部分释放。后者能够通过长脊髓通路募集肌肉进入复杂的节律性活动。
