Suzuki S, Cox C F, White K C
Departments of Restorative Dentistry and Biomaterials, University of Alabama, Birmingham, School of Dentistry 35294-0007.
Quintessence Int. 1994 Jul;25(7):477-85.
This study evaluated the acute pulpal healing response following preparation, etching, and sealing of the prepared vital dentin with a 4-methacryloxyethyl trimellitate anhydride (4-META) bonding system. Adult monkey teeth received crown preparations with chamfer margins, prepared with a diamond used at ultra high speed with water cooling. Vital dentin was etched with 10% citric acid-3% ferric chloride, rinsed, and sealed with 4-META system. A provisional crown was formed with a low-viscosity light-curing adhesive resin. Teeth were fixed and evaluated histopathologically. Pulpal responses at 3 days showed only minimal disruption of the odontoblastic zone. At 7 days, the pulps presented reorganizing odontoblastoid cells, and, at 10 days, the pulps showed new odontoblastoid cells with a thin rim of reparative dentin. Pulps of crown preparations that were etched and then sealed with the 4-META system presented healing patterns similar to those of pulps associated with Class V preparations lined with calcium hydroxide, observed in (previous) similar studies.
本研究评估了使用偏苯三酸三（4-甲基丙烯酰氧乙酯）（4-META）粘结系统对制备后的活髓牙本质进行预备、酸蚀和封闭后牙髓的急性愈合反应。成年猴牙进行了带倒角边缘的全冠预备，使用带水冷装置的超高速金刚石车针进行制备。用10%柠檬酸-3%氯化铁对活髓牙本质进行酸蚀，冲洗后用4-META系统封闭。用低粘度光固化粘结树脂制作临时冠。将牙齿固定并进行组织病理学评估。3天时牙髓反应仅表现为成牙本质细胞层的轻微破坏。7天时，牙髓出现成牙本质细胞样细胞的重新排列，10天时，牙髓可见新的成牙本质细胞样细胞及薄的修复性牙本质边缘。在（之前的）类似研究中观察到，经酸蚀后用4-META系统封闭的全冠预备牙齿的牙髓愈合模式，与用氢氧化钙垫底的V类洞预备相关牙髓的愈合模式相似。
