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[醋酸亮丙瑞林治疗重度子宫内膜异位症]

[Advanced endometriosis treatment with leuprolide acetate].

作者信息

Valdés P, Sierralta P

机构信息

Facultad de Medicina, Universidad de la Frontera, Hospital Regional de Temuco.

出版信息

Rev Chil Obstet Ginecol. 1993;58(5):405-10.

PMID:7991863
Abstract

Endometriosis is a disease observed in women in fertile age, it causes pelvic pain characterized by dysmenorrea and dyspareunia. Moreover, there is an association with infertility. Between the alternative of the medical therapeutics of endometriosis drugs with hipogonadotrofic and hypoestrogenic effects, as the danazol and gestrinona has been used. At present, there are analogies of GnRH factor where leuprolide acetate allow a continue liberation in a monthly administration. This is a case of a woman with extensive endometriosis that has hepatitis due to danazol and subsequently was treated with leuprolide acetate. The effectiveness of leuprolide acetate is analyzed in relation with the relief of pain and the laparoscopic evaluation of the endometriosis focus.

摘要

子宫内膜异位症是一种在育龄期女性中观察到的疾病,它会导致以痛经和性交困难为特征的盆腔疼痛。此外,它还与不孕有关。在具有促性腺激素减退和雌激素减退作用的子宫内膜异位症药物的医学治疗选择中,已使用了达那唑和孕三烯酮。目前,有GnRH因子类似物,其中醋酸亮丙瑞林允许每月给药一次持续释放。这是一个患有广泛子宫内膜异位症且因达那唑导致肝炎的女性病例,随后用醋酸亮丙瑞林进行了治疗。分析了醋酸亮丙瑞林在缓解疼痛和对子宫内膜异位症病灶进行腹腔镜评估方面的有效性。

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