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[体外受精程序的简化管理]

[Simplified management of an in vitro fertilization program].

作者信息

Hess R, Roblero L, Triantafilo Y, Stein C, Alam V, Parada M

机构信息

Departamento de Obstetricia y Ginecología, Clínica Alemana, Santiago.

出版信息

Rev Chil Obstet Ginecol. 1993;58(6):450-4.

PMID:7991869
Abstract

The development of in vitro fertilization has accelerated in a dramatic way the understanding on gamete physiology. Results obtained with the technique are easily reproducible and consistent between different centers. It is well known that cumulative pregnancy rates with 5 or 6 cycles can reach up to 60% of couples being pregnant. However, the main limitations to successive attempts have been the cost of the procedure and the surgical transfer of the embryos. In an attempt to overcome this difficulties, efforts has been made to simplify the monitoring of induction of ovulation, use of GnRh analogs and non surgical transfers whenever it is possible. Results presented in 47 of these cycles show non significant differences, with data published elsewhere, on oocyte maturity, fertilization and cleavage rates. Moreover pregnancy rates per aspiration are 28.6% and per transfer 33.3%. We can conclude that ultrasonography alone to monitor ovulation induction as well as uterine transfers do not affect the outcome of the cycle.

摘要

体外受精的发展极大地加速了对配子生理学的理解。该技术所获得的结果易于重现,且在不同中心之间具有一致性。众所周知,经过5至6个周期的累积妊娠率可达60%的夫妇怀孕。然而,连续尝试的主要限制在于该程序的成本以及胚胎的手术移植。为了克服这些困难,人们已努力尽可能简化排卵诱导监测、GnRh类似物的使用以及非手术移植。这些周期中的47个周期所呈现的结果表明,在卵母细胞成熟、受精和分裂率方面,与其他地方发表的数据相比无显著差异。此外,每次抽吸的妊娠率为28.6%,每次移植的妊娠率为33.3%。我们可以得出结论,仅用超声检查来监测排卵诱导以及子宫内移植不会影响周期的结果。

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Rev Chil Obstet Ginecol. 1993;58(6):450-4.
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