Chazova I E, Belenkov Iu N, Mareev V Iu, Floria V G, Sinitsyn V E, Nakonechnikov S N
Ter Arkh. 1994;66(9):54-7.
Spirometry and bicycle ergometry were performed before and 3 weeks, 6 months after lomir treatment (mean dose 10.62 +/- 2.59 mg/day) of 8 patients with primary pulmonary hypertension. It was found that 3 weeks of the treatment produced a significant increase in the maximum power working capacity and performance, in 6 months of the treatment there were positive trends in gas exchange: anaerobic threshold became higher and maximum oxygen consumption rose. Thus, lomir is recommended for management of primary pulmonary hypertension as it improves exercise tolerance and gas exchange measured by means of spirometry and bicycle ergometry useful both for evaluating functional condition of the patients and the disease advance as well as its response to the therapy conducted.
对8例原发性肺动脉高压患者在接受洛米林治疗（平均剂量10.62±2.59毫克/天）前以及治疗后3周、6个月进行了肺活量测定和自行车测力计测试。结果发现，治疗3周后最大工作能力和表现显著提高，治疗6个月后气体交换出现积极趋势：无氧阈值升高，最大耗氧量增加。因此，推荐使用洛米林治疗原发性肺动脉高压，因为它可改善运动耐量以及通过肺活量测定和自行车测力计测试所测得的气体交换，这对于评估患者的功能状况、疾病进展及其对所进行治疗的反应均有用。
