Bülow S L, Hansen U S, Hansen D, Pedersen F K, Herlin T, Jacobsen J R, Dørup J G
Børneafdeling GGK, Rigshospitalet, København.
Ugeskr Laeger. 1994 Aug 22;156(34):4813-6.
The aim of the study was to estimate the incidence of Kawasaki's disease and to describe the clinical manifestations and the prognosis of the disease in children in Denmark during the period 1981-1990. In a register of all hospital admissions in Denmark, 99 patients were registered as having Kawasaki's disease. Of those, 89 patients fulfilled the clinical diagnostic criteria. The mean incidence of the ten year period was 1.0 per 100,000 children per year. The incidence of the disease decreased in the age group from zero to seven years after which it was rarely observed. Typical laboratory findings were hypersedimentation, leucocytosis and thrombocytosis. Eight children had cardiomegaly and three had electrocardiographic changes. Echocardiography was performed in 66 patients showing coronary artery aneurysms in nine patients (14%) (six boys and three girls). No further cardiac complications were found.
该研究的目的是估算川崎病的发病率,并描述1981年至1990年期间丹麦儿童川崎病的临床表现及预后情况。在丹麦所有住院病例登记册中,有99名患者登记患有川崎病。其中,89名患者符合临床诊断标准。十年期间的平均发病率为每年每10万名儿童中有1.0例。该疾病在0至7岁年龄组中的发病率下降,此后很少观察到。典型的实验室检查结果为血沉加快、白细胞增多和血小板增多。8名儿童有心脏扩大,3名儿童有心电图改变。对66名患者进行了超声心动图检查,其中9名患者(14%)(6名男孩和3名女孩)显示有冠状动脉瘤。未发现进一步的心脏并发症。