Dam H, Mellerup E T
Psykiatrisk afdeling, Rigshospitalet, København.
Ugeskr Laeger. 1994 Oct 10;156(41):5994-8.
Winter depression (Seasonal Affective Disorder, SAD) is a depressive illness, which starts in the autumn and disappears in the spring. The depression is, in contrast to the typical endogenous depression, characterized by increased appetite with carbohydrate craving, and increased sleep. There is an increase in the frequency of the illness towards the geographical poles. About 80% of the patients are women. The most remarkable aspect of the depression is however, that it can be effectively treated with bright light, given two hours daily for one to two weeks. A number of biological functions are currently under investigation in relation to winter depressions; among these are the metabolism of melatonin, various diurnal rhythms and the serotonergic system.
冬季抑郁症(季节性情感障碍,SAD)是一种抑郁症,始于秋季,在春季消失。与典型的内源性抑郁症不同,这种抑郁症的特征是食欲增加并渴望碳水化合物,以及睡眠增加。该病在地理两极的发病频率有所上升。约80%的患者为女性。然而,这种抑郁症最显著的一点是,每天给予两小时的强光照射,持续一到两周,就可以得到有效治疗。目前正在研究与冬季抑郁症相关的一些生物学功能;其中包括褪黑素的代谢、各种昼夜节律和血清素能系统。