Caramatti C, Mangoni L, Carlo-Stella C, Rizzoli V
Department of Hematology, University of Parma.
Acta Biomed Ateneo Parmense. 1993;64(5-6):213-20.
At least three factors may be responsible for leukemic relapse in patients receiving ABMT: (a) minimal residual disease; (b) leukemic cells reinfused with the graft; and (c) the lack of a graft-versus leukemia effect. Techniques for pharmacological marrow decontamination, clinical result obtained with ABMT and the efficacy of ABMT with mafosfamide purged marrow in patients with acute myelogenous leukemia are reviewed.
接受自体骨髓移植（ABMT）的患者白血病复发可能至少由三个因素导致：（a）微小残留病；（b）随移植物回输的白血病细胞；以及（c）缺乏移植物抗白血病效应。本文综述了药理学骨髓净化技术、ABMT取得的临床结果以及马磷酰胺净化骨髓的ABMT在急性髓性白血病患者中的疗效。
