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当归低分子量多糖的免疫药理学研究

Immunopharmacological studies of low molecular weight polysaccharide from Angelica sinensis.

作者信息

Choy Y M, Leung K N, Cho C S, Wong C K, Pang P K

机构信息

Department of Biochemistry, Chinese University of Hong Kong, Shatin, N.T.

出版信息

Am J Chin Med. 1994;22(2):137-45. doi: 10.1142/S0192415X94000176.

Abstract

A low molecular weight polysaccharide has been isolated from the rhizome of Angelica sinensis (Oliv.) Diels (Umbelliferaer). It has a molecular weight of approximately 3,000 and consists of protein (4.73%) and carbohydrate (85.85%) of which 5.2% is uronic acid. It shows strong anti-tumor activity on Ehrlich Ascites tumor bearing mice. It also exhibits immunostimulating activities, both in vitro and in vivo.

摘要

从当归(伞形科)的根茎中分离出一种低分子量多糖。其分子量约为3000,由蛋白质(4.73%)和碳水化合物(85.85%)组成,其中5.2%为糖醛酸。它对艾氏腹水癌荷瘤小鼠显示出强大的抗肿瘤活性。它在体外和体内均表现出免疫刺激活性。

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