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腹主动脉瘤与肾癌并存:治疗选择

Coexistent abdominal aortic aneurysm and renal carcinoma: management options.

作者信息

DeMasi R J, Gregory R T, Snyder S O, Gayle R G, Parent F N, Wheeler J R

机构信息

Division of Vascular Surgery, Eastern Virginia Medical School, Norfolk 23510.

出版信息

Am Surg. 1994 Dec;60(12):961-6.

PMID:7992975
Abstract

Renal carcinoma (RCA) presenting in association with abdominal aortic aneurysm (AAA) is extremely rare, with only sporadic case reports previously described. The management of six cases of AAA and concomitant RCA presenting to a single institution from March, 1991 through December, 1993 was reviewed and management options considered. AAAs ranged in size from 4.5-7.0 cm (mean, 5.6 cm). Three left renal carcinomas were resected via a retroperitoneal approach simultaneous to repair of the AAA. One right renal carcinoma was resected in combination with repair of an AAA through a transperitoneal approach. The fifth case was managed by left nephrectomy, followed by interval aneurysmectomy, and the sixth case was managed by nonsurgical methods because of the presence of widely metastatic disease. Renal malignancies included five renal cell carcinomas and one transitional cell carcinoma. Three patients remain free of disease 8-11 months postoperatively, and one patient had metastatic disease detected 19 months postoperatively. Two deaths have occurred; one due to a massive CVA 1 month following a combined aneurysmectomy and left nephrectomy, and a second due to unknown etiology in the patient managed non-surgically. No peripheral vascular or aortic graft related complications have occurred. The treatment of AAA and RCA should be governed by the size of the AAA, the location of the cancer, and the extent of malignant disease. Simultaneous resection is safe and effective in patients with coexistent AAA and renal cancer. Left sided tumors should be resected via a retroperitoneal approach that also provides excellent exposure for simultaneous AAA resection.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

与腹主动脉瘤(AAA)相关的肾癌(RCA)极为罕见,此前仅有零星病例报告。回顾了1991年3月至1993年12月期间在单一机构就诊的6例AAA合并RCA患者的治疗情况,并考虑了治疗方案。AAA大小在4.5 - 7.0厘米之间(平均5.6厘米)。3例左肾癌通过腹膜后途径切除,同时修复AAA。1例右肾癌通过经腹途径与AAA修复联合切除。第5例先进行左肾切除术,随后择期行动脉瘤切除术,第6例因存在广泛转移疾病采用非手术方法治疗。肾恶性肿瘤包括5例肾细胞癌和1例移行细胞癌。3例患者术后8 - 11个月无疾病复发,1例患者术后19个月发现有转移疾病。发生了2例死亡;1例在联合动脉瘤切除术和左肾切除术后1个月因大面积脑血管意外死亡,另1例在非手术治疗的患者中病因不明。未发生外周血管或主动脉移植相关并发症。AAA和RCA的治疗应根据AAA的大小、癌症的位置以及恶性疾病的范围来决定。对于同时存在AAA和肾癌的患者,同期切除是安全有效的。左侧肿瘤应通过腹膜后途径切除,该途径也能为同期AAA切除提供良好的暴露。(摘要截断于250字)

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