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[1例经腹膜内给予顺铂、依托泊苷及EAP疗法治疗的伴有癌性腹膜炎的胃癌根治术病例]

[A case of curatively operated gastric cancer with peritonitis carcinomatosa treated by intraperitoneal administration of CDDP.Etoposide and EAP therapy].

作者信息

Sakata Y, Okamura T, Kurimoto H, Ono K, Uenishi M

机构信息

Dept. of Surgery, Izumiotsu City Hospital.

出版信息

Gan To Kagaku Ryoho. 1994 Dec;21(16):2829-32.

PMID:7993123
Abstract

Intraperitoneal administration of cisplatin (CDDP) etoposide (VP-16) and EAP therapy (combination chemotherapy with CDDP, adriamycin (ADM) and etoposide provided the curative resection for advanced gastric cancer with peritonitis carcinomatosa in a 48-year-old woman. She suffered from epigastralgia. CT shows the ascites, and ultrasonography shows Schnitzler metastasis. First, CDDP 100 mg and etoposide 200 mg were given intraperitoneally. Then, the ascites completely disappeared. Next, the patient underwent EAP therapy, after which Schnitzler metastasis disappeared, and total gastrectomy was performed. Macroscopically, it was of H0P0N0S2. Histopathologically, it was poorly differentiated adenocarcinoma and n0s2. She has been doing well with no evidence of recurrence for 18 months after operation.

摘要

对一名48岁患有腹膜癌性腹膜炎的晚期胃癌女性患者,采用顺铂(CDDP)、依托泊苷(VP - 16)腹腔内给药以及EAP疗法(CDDP、阿霉素(ADM)和依托泊苷联合化疗)实现了根治性切除。她患有上腹部疼痛。CT显示有腹水,超声检查显示有施尼茨勒转移。首先,腹腔内给予顺铂100毫克和依托泊苷200毫克。然后,腹水完全消失。接下来,患者接受EAP疗法,之后施尼茨勒转移消失,并进行了全胃切除术。宏观上,为H0P0N0S2。组织病理学检查为低分化腺癌且n0s2。术后18个月她情况良好,无复发迹象。

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