Bernstein S J, Hilborne L H, Leape L L, Park R E, Brook R H
School of Medicine, University of Michigan, Ann Arbor.
Arch Intern Med. 1994;154(23):2759-65. doi: 10.1001/archinte.1994.00420230156019.
To determine whether there are differences between women and men in the appropriateness of use of cardiovascular procedures.
Retrospective chart review.
Thirty hospitals located in New York State.
Random sample of 3979 patients undergoing coronary angiography, percutaneous transluminal coronary angioplasty, or coronary artery bypass graft surgery in 1990.
We evaluated two measures: (1) the percent of women and men who underwent cardiovascular procedures for appropriate, uncertain, and inappropriate indications and (2) for coronary angiography patients, the prognostic exercise stress treadmill score that predicts before the coronary angiogram the 5-year probability of death from a cardiovascular event.
The inappropriate rate of use of cardiovascular procedures was low and not significantly different for men and women (4% vs 5% for coronary angiography; 4% vs 3% for percutaneous transluminal coronary angioplasty; and 2% vs 3% for coronary artery bypass graft surgery, respectively), and the use of these procedures for uncertain reasons also did not vary significantly by gender. There was also no significant gender difference in the predicted risk of death from a cardiovascular event for coronary angiography patients: 24% of men and 22% of women were at high risk (ie, < 75% 5-year survival rate) and 20% and 16%, respectively, were at low risk (ie, > or = 95% 5-year survival rate).
Based on two indicators, the RAND appropriateness score and the Duke prognostic exercise treadmill score, we were unable to find any evidence of a difference in the clinical appropriateness of use of these three cardiovascular procedures between women and men.
确定在心血管手术的合理应用方面,男性和女性之间是否存在差异。
回顾性病历审查。
位于纽约州的30家医院。
1990年接受冠状动脉造影、经皮腔内冠状动脉成形术或冠状动脉旁路移植术的3979例患者的随机样本。
我们评估了两项指标:(1)因合理、不确定和不合理指征接受心血管手术的男性和女性的百分比;(2)对于冠状动脉造影患者,在冠状动脉造影前预测心血管事件死亡5年概率的预后运动应激平板评分。
心血管手术的不合理使用率较低,男性和女性之间无显著差异(冠状动脉造影分别为4%对5%;经皮腔内冠状动脉成形术分别为4%对3%;冠状动脉旁路移植术分别为2%对3%),因不确定原因使用这些手术的情况在性别上也无显著差异。冠状动脉造影患者心血管事件死亡预测风险在性别上也无显著差异:24%的男性和22%的女性处于高风险(即5年生存率<75%),分别有20%和16%处于低风险(即5年生存率≥95%)。
基于两个指标,即兰德合理性评分和杜克预后运动平板评分,我们未能找到任何证据表明男性和女性在这三种心血管手术的临床合理应用方面存在差异。