Association of isoimmune thrombocytopenia and neonatal hyperinsulinism/hypoglycemia.

Neonatal hyperinsulinism and hypoglycemia have a well-established association with maternal Rh isoimmunization. We report herein an infant who presented with significant neonatal hypoglycemia that was found to be secondary to hyperinsulinism and who also had thrombocytopenia secondary to maternal platelet isoimmunization.