Ichimaru Y, Katayama S
Department of Neurology, Dokkyo University School of Medicine, Shimotsuga, Japan.
Front Med Biol Eng. 1994;6(2):117-30.
We have developed a system to analyze heart rate variability (HRV) (power spectral array of the HRV) during 24 h ambulatory electrocardiographic monitoring. Several rhythms (circadian and several ultradian rhythms) were observed in the power spectral array of the heart rates and 1/f-like fluctuations in the log-log scaled heart rate power spectrum. The circadian change of the heart rate is closely related to the body temperature rhythm. The 90 min rhythm of HRV during sleep was suspected to be produced by the sleep cycle (REM/NREM) and the lower frequency peak of the HRV was coherent with oscillation in amplitude modulated respiration. These circadian and ultradian rhythm as assessed by heart rate variability exist both in normal subjects and in patients with autonomic failure. The power of the high frequency band decreases in subjects with autonomic failure. The power of low frequency components increases during periodic breathing or Cheyne-Stokes respiration. Log-log scaled analysis of the power spectrum of HRV disclosed that the slope of the HRV is markedly modulated by the range of the frequency applied for the least square regression line analysis. The increased power that might be produced by periodic breathing and decreased power in patients with autonomic failure might strongly modulate the slope of the log-log scaled HRV. It is concluded that the power spectral array of the HRV during 24 h period is useful in the detection of circadian and ultradian rhythm, and log-log scaled power spectra might be useful in the overall integration of the heart rate dynamics produced by the central nervous system. The several rhythm factors that might be produced by the central nervous system might modulate 1/f fluctuations of the HRV.
我们开发了一种系统，用于在24小时动态心电图监测期间分析心率变异性（HRV）（HRV的功率谱阵列）。在心率的功率谱阵列中观察到几种节律（昼夜节律和几种超日节律）以及对数-对数标度心率功率谱中的1/f样波动。心率的昼夜变化与体温节律密切相关。睡眠期间HRV的90分钟节律被怀疑是由睡眠周期（快速眼动/非快速眼动）产生的，并且HRV的低频峰值与调幅呼吸的振荡相关。通过心率变异性评估的这些昼夜节律和超日节律在正常受试者和自主神经功能衰竭患者中均存在。自主神经功能衰竭患者的高频带功率降低。在周期性呼吸或潮式呼吸期间，低频成分的功率增加。HRV功率谱的对数-对数标度分析表明，HRV的斜率受到用于最小二乘回归线分析的频率范围的显著调节。周期性呼吸可能产生的功率增加以及自主神经功能衰竭患者的功率降低可能会强烈调节对数-对数标度HRV的斜率。得出的结论是，24小时期间HRV的功率谱阵列有助于检测昼夜节律和超日节律，并且对数-对数标度功率谱可能有助于对中枢神经系统产生的心率动态进行整体整合。中枢神经系统可能产生的几种节律因素可能会调节HRV的1/f波动。
