Alejandro D S, Petersen J
Division of Nephrology, Stanford University School of Medicine, CA 94305-5114.
J Am Soc Nephrol. 1994 Aug;5(2):153-60. doi: 10.1681/ASN.V52153.
Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed.
心脏移植患者可能因多种原因发生急性肾衰竭。本文报告了一例继发于药物性横纹肌溶解的急性肾衰竭患者。本文回顾了有关急性肾衰竭与洛伐他汀及其他3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂的文献。讨论了肌红蛋白尿和肾毒性的潜在机制及其治疗意义。
