Piattelli A, Artese L
Dental School, University of Chieti, Italy.
Bull Group Int Rech Sci Stomatol Odontol. 1994 Mar-Jun;37(1-2):27-30.
A large portion of periapical granulomas is composed by cells of the mononuclear-phagocyte and lymphoid system. The ultrastructural features of the monocytes/macrophages differ in relationship to the state of activity of the cells (phagocytosis or secretion). A close correlation between cells of these two systems can be surmised by their tight contacts. An important role in the bone resorption is probably played by cytokines like IL-1 and TNF.
大部分根尖周肉芽肿由单核吞噬细胞和淋巴系统的细胞组成。单核细胞/巨噬细胞的超微结构特征因细胞的活性状态（吞噬或分泌）而异。这两个系统的细胞之间紧密接触，由此可推测它们之间存在密切关联。白细胞介素-1和肿瘤坏死因子等细胞因子可能在骨吸收中起重要作用。
