Abbo K M, Carroll J D
Department of Medicine, University of Chicago, Illinois.
Cathet Cardiovasc Diagn. 1994;Suppl 2:16-25.
This review discusses the latest developments in the hemodynamics of mitral stenosis. English-language journal articles, reviews, and textbooks from the clinical, physiology, and engineering literature related to mitral valve stenosis were identified and reviewed. The main conclusions are: (1) the hemodynamics of mitral stenosis are determined by the complex anatomical and pathophysiologic features of the valve apparatus, (2) the properties of the left ventricle, atrium, and pulmonary vasculature also have a major impact on the hemodynamic significance and the clinical syndrome of mitral stenosis, (3) the valve and the cardiac chambers have a functional reserve that become exhausted as the stenosis worsens and/or the compensatory mechanisms of the chambers fail, and (4) a careful approach to data acquisition and analysis will lead to an accurate assessment of the hemodynamics of mitral stenosis before and after therapeutic interventions.
本综述讨论了二尖瓣狭窄血流动力学的最新进展。我们检索并综述了临床、生理学和工程学文献中与二尖瓣狭窄相关的英文期刊文章、综述及教科书。主要结论如下：（1）二尖瓣狭窄的血流动力学由瓣膜装置复杂的解剖和病理生理特征决定；（2）左心室、心房及肺血管系统的特性对二尖瓣狭窄的血流动力学意义及临床综合征也有重大影响；（3）瓣膜及心腔具有功能储备，随着狭窄加重和/或心腔代偿机制失效，该储备会被耗尽；（4）谨慎的数据采集和分析方法将有助于在治疗干预前后准确评估二尖瓣狭窄的血流动力学情况。
