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血浆肾素浓度以及苄氟噻嗪和阿替洛尔的降压作用。

Plasma renin concentration and the hypotensive effect of bendrofluazide and of atenolol.

作者信息

Fagard R, Amery A, Deplaen J F, Lijnen P, Missotten A

出版信息

Clin Sci Mol Med Suppl. 1976 Dec;3:215s-217s. doi: 10.1042/cs051215s.

Abstract
  1. The anti-hypertensive effect of atenolol was greater than that of bendrofluazide. 2. The change in systolic blood pressure caused by bendrofluazide showed a significant inverse correlation iwth the plasma renin concentration (r=-0-47; P less than 0-01). 3. The correlation between the change in systolic blood pressure caused by atenolol and the plasma renin concentration was not significant (r =0-28; 0-1 greater than P greater than 0-05). 4. Plasma renin concentration was unaffected by atenolol.
摘要
  1. 阿替洛尔的降压效果强于苄氟噻嗪。2. 苄氟噻嗪引起的收缩压变化与血浆肾素浓度呈显著负相关(r = -0.47;P < 0.01)。3. 阿替洛尔引起的收缩压变化与血浆肾素浓度之间的相关性不显著(r = 0.28;0.1 > P > 0.05)。4. 阿替洛尔对血浆肾素浓度无影响。

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