Behar S, Hod H, Benari B, Narinsky R, Pauzner H, Rechavia E, Faibel H, Katz A, Roth A, Goldhammer E
Israel Thrombolytic Study Group, Neufeld Cardiac Research Institute, Chaim Sheba Medical Center, Tel Hashomer.
Harefuah. 1994 Nov 15;127(10):361-4, 432.
Whether the presence of on-site coronary angiographic facilities (CAF) influences the use of invasive coronary procedures and the outcome of acute myocardial infarction in coronary care units was studied. A prospective survey was conducted early in 1992 when 1014 consecutive patients with acute infarction were admitted. Of them 707 (70%) were admitted to coronary care units of hospitals with, and 307 (30%) without CAF. Thrombolytic therapy was given to 46% in both groups. Those admitted to hospitals with CAF underwent more coronary angiographies (26%) and percutaneous transluminal angiography and/or coronary artery bypass grafting (12%) than those without CAF (10 and 5%, respectively--p < 0.005). In-hospital and 1-year mortality were 11 and 18% respectively in those with CAF, vs 10 and 11%, respectively, in those without CAF. All patients treated with a thrombolytic agent had similar mortality, unrelated to the availability of CAF. The survey showed that the availability of on-site coronary angiography facilities led to greater use of invasive coronary procedures in cases of acute myocardial infarction, but there was no significant difference in mortality.
研究了现场冠状动脉造影设备(CAF)的存在是否会影响冠心病监护病房中侵入性冠状动脉手术的使用以及急性心肌梗死的治疗结果。1992年初进行了一项前瞻性调查,当时连续收治了1014例急性梗死患者。其中707例(70%)被收治到设有CAF的医院的冠心病监护病房,307例(30%)被收治到没有CAF的医院。两组中均有46%的患者接受了溶栓治疗。与没有CAF的患者相比,被收治到设有CAF的医院的患者接受冠状动脉造影的比例更高(26%),接受经皮腔内血管成形术和/或冠状动脉旁路移植术的比例也更高(12%)(没有CAF的患者分别为10%和5%,p<0.005)。设有CAF的患者院内死亡率和1年死亡率分别为11%和18%,而没有CAF的患者分别为10%和11%。所有接受溶栓治疗的患者死亡率相似,与CAF的可用性无关。该调查表明,现场冠状动脉造影设备的可用性导致急性心肌梗死患者更多地使用侵入性冠状动脉手术,但死亡率没有显著差异。