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苄乙胍、甲基多巴和普萘洛尔治疗高血压的患者内比较

A within-patient comparison of bethanidine, methyldopa and propranolol in the treatment of hypertension.

作者信息

Prichard B N, Boakes A J, Graham B R

出版信息

Clin Sci Mol Med Suppl. 1976 Dec;3:567s-570s. doi: 10.1042/cs051567s.

Abstract
  1. A within-patient comparison showed that bethanidine, methyldopa and propranolol produced similar control of the blood pressure. 2. Unlike bethanidine, propranolol did not produce postural and exercise hypotension; methyldopa was intermediate in effect. 3. Overall side effects were of a similar incidence though there were differences in incidence of particular side effects.
摘要
  1. 患者自身对照显示,苄乙胍、甲基多巴和普萘洛尔对血压的控制效果相似。2. 与苄乙胍不同,普萘洛尔不会引起体位性和运动性低血压;甲基多巴的作用介于两者之间。3. 总体副作用发生率相似,不过特定副作用的发生率存在差异。

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