Glynn P, Higby D, Moriarty E, Ficalora M, Volpe B, Koletsky A, White C
Department of Medicine, Baystate Medical Center, Springfield, MA 01109.
J Med. 1994;25(3-4):193-201.
Twenty-eight evaluable patients were treated with an infusion of cisplatin and etoposide for advanced non-small cell lung cancer. A response was demonstrated in 43%, although only two patients had documented partial responses. The regimen was surprisingly low in toxicity, both acute and chronic, and is suitable for palliation of patients who are elderly or suffer from chronic illnesses which preclude more agressive therapy.
28例可评估患者接受了顺铂和依托泊苷输注治疗晚期非小细胞肺癌。43%的患者显示有反应,尽管只有2例患者有记录的部分缓解。该方案的急性和慢性毒性均出奇地低,适用于老年患者或患有慢性疾病而无法接受更积极治疗的患者的姑息治疗。