新型锌螯合剂，可抑制HIV-EP1（HIV增强子结合蛋白）与NF-κB识别序列的结合。 - Suppr

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超能文献

Novel zinc chelators which inhibit the binding of HIV-EP1 (HIV enhancer binding protein) to NF-kappa B recognition sequence.

作者信息

Otsuka M, Fujita M, Sugiura Y, Ishii S, Tsutomu A, Yamamoto T, Inoue J I

机构信息

Institute for Chemical Research, Kyoto University, Japan.

出版信息

J Med Chem. 1994 Dec 9;37(25):4267-9. doi: 10.1021/jm00051a002.

DOI:10.1021/jm00051a002

PMID:7996537

Abstract

摘要

相似文献

Novel zinc chelators which inhibit the binding of HIV-EP1 (HIV enhancer binding protein) to NF-kappa B recognition sequence.新型锌螯合剂，可抑制HIV-EP1（HIV增强子结合蛋白）与NF-κB识别序列的结合。

J Med Chem. 1994 Dec 9;37(25):4267-9. doi: 10.1021/jm00051a002.

Novel zinc chelators with dual activity in the inhibition of the kappa B site-binding proteins HIV-EP1 and NF-kappa B.具有抑制κB位点结合蛋白HIV-EP1和核因子κB双重活性的新型锌螯合剂。

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Metal-chelating inhibitors of a zinc finger protein HIV-EP1. Remarkable potentiation of inhibitory activity by introduction of SH groups.锌指蛋白HIV-EP1的金属螯合抑制剂。通过引入SH基团显著增强抑制活性。

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Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism.人硫氧还蛋白/成人T细胞白血病衍生因子通过硫醇氧化还原控制机制激活1型人类免疫缺陷病毒的增强子结合蛋白。

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NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro.NF-κB介导的体外HIV-1增强子染色质重排及转录激活

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Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription.用抗CD3或肿瘤坏死因子刺激人T细胞克隆可诱导核因子-κB易位，但不能诱导人免疫缺陷病毒1增强子依赖性转录。

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DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs.DNA CpG甲基化抑制NF-κB蛋白与HIV-1长末端重复序列同源DNA基序的结合。

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Modulation of HIV-1 enhancer activity and virus production by cAMP.环磷酸腺苷（cAMP）对HIV-1增强子活性和病毒产生的调节作用

FEBS Lett. 2001 Dec 7;509(2):207-12. doi: 10.1016/s0014-5793(01)03182-9.

Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.硫醇试剂和Bcl-2确定了一种由甲病毒诱导的凋亡途径，该途径需要转录因子NF-κB的激活。

J Cell Biol. 1995 Dec;131(5):1149-61. doi: 10.1083/jcb.131.5.1149.

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Molecules. 2020 Oct 28;25(21):4984. doi: 10.3390/molecules25214984.

SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus.SRR-SB3，一种含二硫键的大环内酯类化合物，可抑制人类免疫缺陷病毒复制周期的晚期阶段。

Antimicrob Agents Chemother. 1997 Feb;41(2):262-8. doi: 10.1128/AAC.41.2.262.

The in vitro ejection of zinc from human immunodeficiency virus (HIV) type 1 nucleocapsid protein by disulfide benzamides with cellular anti-HIV activity.具有细胞抗HIV活性的二硫代苯甲酰胺对人免疫缺陷病毒1型核衣壳蛋白的体外锌离子释放作用

Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):969-73. doi: 10.1073/pnas.93.3.969.

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