Lemasters G K
Wydziału Zdrowia Srodowiskowego w Cincinnati.
Med Pr. 1994;45(5):419-33.
Methodological problems of epidemiological studies of the effect of harmful factors present in the working environment on the reproduction and development of the progeny were discussed. Basic types of epidemiological studies such as retrospective and prospective cohort studies, cross-sectional and case-control studies were presented. Issues pertaining to the measurement bias and its sources in individual types of studies were raised. An appropriate selection of measures illustrating disturbances in the reproduction and development of the progeny was considered as well as adapted definitions of those measures and their correct classification. ahe methodology of an appropriate assessment of exposure to harmful factors in the working environment was also discussed.
讨论了工作环境中有害因素对后代生殖和发育影响的流行病学研究的方法学问题。介绍了流行病学研究的基本类型，如回顾性和前瞻性队列研究、横断面研究和病例对照研究。提出了与个体研究类型中的测量偏差及其来源相关的问题。考虑了对说明后代生殖和发育障碍的指标进行适当选择，以及这些指标的适应性定义及其正确分类。还讨论了对工作环境中有害因素暴露进行适当评估的方法。
