Barat J L, Benabid A, Blond S, Brunon J, Chazal J, Cohadon F, Devaux B, Eperonnat E, Gambarelli D, Hor F
Département de neurochirurgie, CHRU La Timone, Marseille.
Neurochirurgie. 1994;40(1):3-9.
370 stereotactic biopsies of pineal region tumors, from 15 neurosurgical centers in France have been reviewed with the goal to evaluate the mortality/morbidity rates and diagnostic yield of this procedure. The impact of neuroradiological means of localisation, the probe trajectory, the type of biopsy instrument, the time of shunting are discussed in order to maximize the diagnostic yield and minimize the mortality/morbidity rates. Stereotactic biopsy contribution, as compared to other diagnostic methods, in pineal region tumors was evaluated. The mortality rate was 1.3 % (5 patients of 370), 3 patients suffered severe neurological complication. In relation to the large number of patients in this study, we can assess that the mortality rate of stereotactic biopsy in this region doesn't significantly exceed that of stereotactic brain tumor biopsies in general.
对来自法国15个神经外科中心的370例松果体区肿瘤立体定向活检病例进行了回顾,目的是评估该手术的死亡率/发病率以及诊断率。讨论了神经放射定位方法、穿刺针轨迹、活检器械类型、分流时间的影响,以最大限度提高诊断率并降低死亡率/发病率。评估了立体定向活检与其他诊断方法相比在松果体区肿瘤中的作用。死亡率为1.3%(370例中有5例),3例出现严重神经并发症。鉴于本研究中的患者数量众多,我们可以认为该区域立体定向活检的死亡率并未显著超过一般立体定向脑肿瘤活检的死亡率。