Chun M, Timmerman R D, Mayer R, Ling M N, Sheldon J, Fishman E K
Department of Radiation Oncology, Ajou University Hospital, Suwŏn, South Korea.
Radiology. 1995 Jan;194(1):147-50. doi: 10.1148/radiology.194.1.7997542.
To determine whether "standard" lateral pelvic radiation therapy portals provide adequate margins for treating the external iliac lymph nodes (EILNs).
With computed tomographic (CT) data and a computerized algorithm, the course of the EILN chain was reconstructed in 48 patients. The marginal distance between a consistently localized portion of the EILNs and the anterior field border that was placed at the front of the pubic symphysis was recorded for each patient.
The EILNs were covered adequately in only 50% of both men and women. More adequate EILN margins were observed in (a) women older than 68 years, (b) women with small anteroposterior separations, (c) men older than 70 years, and (d) men and women with a low central obesity index. Less adequate margins were observed in men who were obese or men with large anteroposterior separations. In the study population, no correlation was observed for sex, race, or tumor site.
The authors recommend portals that are designed specifically for patients rather than standard portals that may inadequately cover the intended targets.
确定“标准”的盆腔侧方放射治疗野是否能为治疗髂外淋巴结（EILNs）提供足够的边界。
利用计算机断层扫描（CT）数据和计算机算法，对48例患者的EILN链走行进行重建。记录每位患者EILNs始终定位部分与置于耻骨联合前方的前野边界之间的边缘距离。
男性和女性中仅有50%的患者EILNs得到充分覆盖。在以下情况中观察到更充分的EILN边界：（a）68岁以上女性；（b）前后径较小的女性；（c）70岁以上男性；（d）中心肥胖指数较低的男性和女性。肥胖男性或前后径较大的男性的边界覆盖较差。在研究人群中，未观察到性别、种族或肿瘤部位之间的相关性。
作者推荐为患者专门设计的放射野，而非可能无法充分覆盖预期靶区的标准放射野。
