Battolla L, Zampa V, Mascalchi M, Falaschi F, Bagnolesi P, Tessa C, Paolicchi A, Bartolozzi C
Cattedra di Radiologia, Università di Pisa.
Radiol Med. 1994 Oct;88(4):353-8.
Combination of fat suppression techniques with intravenous paramagnetic contrast administration is usually performed using high-field MR systems. We combined a modified three-point Dixon technique for fat suppression with gadolinium-DTPA administration in the investigation of soft tissue neoplasms at 0.5 T. Nineteen patients with 21 neoplasms (14 primary malignant, 2 metastatic, 5 benign tumors) were examined. Examination protocol included unenhanced SE T1, PD and T2-weighted images. After the intravenous administration of gadolinium-DTPA (0.1 mmol/kg), a modified three-point Dixon technique provided three image sets, i.e., conventional T1-weighted SE images, fat-suppressed T1-weighted images and water-suppressed T1-weighted images. Two observers evaluated the lesions for conspicuity and size in three image groups: unenhanced T1-, PD and T2-weighted images, enhanced conventional T1-weighted images, enhanced T1-weighted images with fat suppression. Ten lesions showed greater conspicuity on enhanced fat-suppressed images than on unenhanced T1-, PD and T2- and enhanced conventional T1-weighted images. In 16 cases lesions were more conspicuous on enhanced water images than on conventional enhanced T1 images. Ten tumors exhibited a larger size (difference exceeding 20%) on enhanced fat-suppressed images. The combination of gadolinium with the modified Dixon technique improves the demonstration of soft tissue neoplasms at 0.5 T and allows lesion size to be measured more accurately.
脂肪抑制技术与静脉注射顺磁性对比剂相结合通常使用高场强磁共振系统来进行。我们在0.5T场强下将一种改良的三点式狄克逊脂肪抑制技术与钆喷酸葡胺注射相结合,用于软组织肿瘤的研究。对19例患有21个肿瘤(14个原发性恶性肿瘤、2个转移性肿瘤、5个良性肿瘤)的患者进行了检查。检查方案包括未增强的SE T1、PD和T2加权图像。静脉注射钆喷酸葡胺(0.1 mmol/kg)后,改良的三点式狄克逊技术提供了三组图像,即传统的T1加权SE图像、脂肪抑制T1加权图像和水抑制T1加权图像。两名观察者在三个图像组中评估病变的清晰度和大小:未增强的T1、PD和T2加权图像、增强的传统T1加权图像、脂肪抑制的增强T1加权图像。10个病变在增强的脂肪抑制图像上比在未增强的T1、PD和T2以及增强的传统T1加权图像上显示出更高的清晰度。在16例中,病变在增强水图像上比在传统增强T1图像上更明显。10个肿瘤在增强的脂肪抑制图像上显示出更大的尺寸(差异超过20%)。钆与改良狄克逊技术的结合提高了0.5T场强下软组织肿瘤的显示效果,并能更准确地测量病变大小。