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[Peroxide radicals in the metabolism of toxic substances].

作者信息

Proca M, Agoroaei L, Butnaru E, Cotrău M

机构信息

Disciplina de Toxicologie, Universitatea de Medicină şi Farmacie Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1993 Apr-Jun;97(2):287-90.

PMID:7997674
Abstract

The free radicals resulting from the metabolism of oxygen and some xenobiotics, can induce, when a limit concentration is exceeded, toxic effects due to their action on DNA, enzymes and fatty acids. Therefore, the association of oxygen therapy with drug administration may have a more or less beneficial effect. Thus, in a long-term treatment with drugs which by metabolized release free radicals, the use of exogenous compounds for protecting the human body need to be administered.

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