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[心脏移植或心肌成形术患者选择的动态变化]

[Dynamics of patient selection for heart transplantation or cardiomyoplasty].

作者信息

de Freitas H F, Nastari L, Mansur A J, Bocchi E A, Moreira L F, Bacal F, Barretto A C, Stolf N A, Bellotti G

机构信息

Instituto do Coração do Hospital das Clínicas-FMUSB, São Paulo.

出版信息

Arq Bras Cardiol. 1994 Apr;62(4):233-7.

PMID:7998849
Abstract

PURPOSE

To evaluate patient selection for heart transplantation or dynamic cardiomyoplasty.

METHODS

We evaluated 380 patients from April 1991 to July 1993. The ages ranged between 16 and 68 (mean 43.5 +/- 11.46) years, 303 (79.7%) were male. The diagnoses were dilated cardiomyopathy in 163 (42.9%), Chagas' cardiomyopathy in 70 (18.4%), ischemic heart disease in 61 (16.1%), hypertensive heart disease in 40 (10.5%), valvular heart disease in 23 (6.1%), alcoholic cardiomyopathy in 12(3.2%), peripartum cardiomyopathy in 5 (1.3%) and myocarditis of unknown etiology in 5 (1.3%).

RESULTS

The indication of heart transplantation was eventually done in 55 (14.4%), and 19 (5%) were submitted to transplantation. Dynamic cardiomyoplasty was indicated in 9 (2.3%) patients and was performed in 8 (2.1%). In 30 (7.8%) patients there were clinical contraindications for transplantation. Conventional surgical treatment was indicated for 12 (3.1%) patients: myocardial revascularization and/or ventricular aneurismectomy in 5, surgical treatment of valvular heart disease in 6 and of atrial fibrillation in 1. Socioeconomic limitations precluded transplantation in 43 (11.3%) and psychic limitations hindered transplantation in 23 (6.0%) patients. Refusal of procedure by the patient occurred in 10 (2.6%) cases. Improvement of the symptoms occurred in 69 (18.1%) patients.

CONCLUSION

A small percentage of patients are eligible and are eventually submitted to heart transplantation or dynamic cardiomyoplasty. New strategies may be delineated during follow up, as deferring transplantation or conventional surgical treatment of ischemic or valvular heart disease. Sociopsychic evaluation is an important step in the care of the patients.

摘要

目的

评估心脏移植或动态心肌成形术的患者选择。

方法

我们对1991年4月至1993年7月期间的380例患者进行了评估。年龄在16至68岁之间(平均43.5±11.46岁),其中303例(79.7%)为男性。诊断结果为:扩张型心肌病163例(42.9%),恰加斯心肌病70例(18.4%),缺血性心脏病61例(16.1%),高血压性心脏病40例(10.5%),瓣膜性心脏病23例(6.1%),酒精性心肌病12例(3.2%),围产期心肌病5例(1.3%),病因不明的心肌炎5例(1.3%)。

结果

最终55例(14.4%)患者有心脏移植指征,其中19例(5%)接受了移植。9例(2.3%)患者有动态心肌成形术指征,8例(2.1%)接受了该手术。30例(7.8%)患者存在移植的临床禁忌证。12例(3.1%)患者需进行传统手术治疗:5例行心肌血运重建和/或室壁瘤切除术,6例行瓣膜性心脏病手术,1例行房颤手术。社会经济限制使43例(11.3%)患者无法进行移植,心理限制使23例(6.0%)患者无法进行移植。10例(2.6%)患者拒绝手术。69例(18.1%)患者症状改善。

结论

符合条件并最终接受心脏移植或动态心肌成形术的患者比例较小。在随访期间可能会制定新的策略,如推迟缺血性或瓣膜性心脏病的移植或传统手术治疗。社会心理评估是患者护理中的重要一步。

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