Díaz-Alvarenga A, Abasta-Jimenez M, Bravo B, Gamba G, Correa-Rotter R
Department of Nephrology and Mineral Metabolism, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico DF, Mexico.
Adv Perit Dial. 1994;10:47-51.
The peritoneal equilibration test (PET) is used as a tool for dialysis prescription. In order to establish which parameters can predict peritoneal transport type, we studied 55 patients on continuous ambulatory peritoneal dialysis (CAPD), who were subjected to a standard PET. Clinical data (sex, age, calculated body surface area [BS], average time on dialysis [TD], and presence of diabetes mellitus), laboratory variables, (serum creatinine [SCr] blood urea nitrogen [BUN], serum albumin [SA], and residual renal function), and adequacy parameters (dialysate creatinine clearance [CrCl], weekly clearance of urea normalized to total body water [KT/V], protein catabolic rate, and dialysis index), were obtained and recorded at the time of the PET. The study group was composed of 29 males and 26 females, mean age of 43.5 +/- 16 years, and average TD of 25.2 +/- 18 months. PET results: 13 patients were low, 16 low average, 19 high average, and 7 high peritoneal transporters. According to the logistic regression analysis, the factors significantly associated with the type of peritoneal transport were: BS, SA, dialysate CrCl, and TD (coefficients 7.2, -1.23, 0.72, and -0.03, respectively). Greater BS and lower SA directly correlate with high peritoneal transport, and are the strongest predictors for the model.
腹膜平衡试验（PET）用作透析处方的一种工具。为了确定哪些参数可以预测腹膜转运类型，我们研究了55例接受持续性非卧床腹膜透析（CAPD）的患者，这些患者接受了标准的PET检查。在PET检查时获取并记录临床数据（性别、年龄、计算得出的体表面积[BS]、透析平均时间[TD]以及糖尿病的存在情况）、实验室变量（血清肌酐[SCr]、血尿素氮[BUN]、血清白蛋白[SA]以及残余肾功能）和充分性参数（透析液肌酐清除率[CrCl]、根据总体水标准化的每周尿素清除率[KT/V]、蛋白质分解代谢率以及透析指数）。研究组由29名男性和26名女性组成，平均年龄为43.5±16岁，平均TD为25.2±18个月。PET结果：13例患者为低转运，16例为低平均转运，19例为高平均转运，7例为高腹膜转运。根据逻辑回归分析，与腹膜转运类型显著相关的因素为：BS、SA、透析液CrCl和TD（系数分别为7.2、-1.23、0.72和-0.03）。更大的BS和更低的SA与高腹膜转运直接相关，并且是该模型最强的预测因素。
