Zhao D, Yamaguchi R, Tateyama S, Ogawa H, Yamazaki Y
Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University, Japan.
J Vet Med Sci. 1994 Aug;56(4):753-5. doi: 10.1292/jvms.56.753.
Disseminated hemangiosarcoma was encountered in a 12-year-old female Maltese dog. Tumor tissues were dispersed on the serosal surface of the liver, kidney, digestive tract, omentum and diaphragm. Metastatic lesions were not observed in the parenchyma of the lung and heart. The spleen was enlarged with rupture at the anterior region of the hilus. The disseminated protruding tumor masses could be easily peeled off from the organ surfaces. The tumor cells were round or spindle in shape, with hyperchromatic nuclei containing prominent nucleoli. Various-sized vascular spaces containing erythrocytes and serum could be identified in this tumor. This case was diagnosed as hemangiosarcoma originating from the spleen with abdominal dissemination.
一只12岁的雌性马尔济斯犬被诊断为弥漫性血管肉瘤。肿瘤组织散布于肝脏、肾脏、消化道、网膜和膈肌的浆膜表面。肺和心脏实质未观察到转移病灶。脾脏肿大，脾门前部破裂。弥漫性突出的肿瘤块很容易从器官表面剥离。肿瘤细胞呈圆形或梭形，细胞核染色质增多，有明显的核仁。在该肿瘤中可识别出含有红细胞和血清的各种大小的血管腔隙。该病例被诊断为起源于脾脏并伴有腹部播散的血管肉瘤。
