Moral A J, Arias J, García M A, Abengózar R, Pérez-Carral C, Senent C J
Sección de Alergología, Hospital Virgen del Valle, Toledo.
Arch Bronconeumol. 1994 Nov;30(9):462-4. doi: 10.1016/s0300-2896(15)31020-6.
We present a case of extrinsic allergic alveolitis due to Penicillium frequentans exposure (suberosis) at a cork factory. Diagnosis was based on clinical history, a restrictive spirometric pattern, evidence of reticular-nodular lung infiltrates on the X-ray, intradermal skin tests with dual reaction and precipitins-positive serum samples in the presence of the P. frequentans fungus. Although the patient refused to submit to a specific bronchial challenge, two natural challenges occurred when he once again happened to handle wet cork after leaving his previous job. The literature referring to this disease is reviewed.
我们报告了一例在软木工厂因接触频繁青霉（橡木尘肺）导致的外源性过敏性肺泡炎病例。诊断基于临床病史、肺功能检查呈现的限制性模式、X线显示的网状结节性肺部浸润、皮内皮肤试验出现的双重反应以及在存在频繁青霉真菌的情况下血清沉淀素呈阳性。尽管患者拒绝接受特定的支气管激发试验，但在他离开上一份工作后再次接触湿软木时发生了两次自然激发试验。本文对有关该疾病的文献进行了综述。
