Herrman J R, Keane D, Ozaki Y, den Boer A, Serruys P W
Department of Interventional Cardiology, Erasmus University, Rotterdam, The Netherlands.
Cathet Cardiovasc Diagn. 1994 Sep;33(1):55-60. doi: 10.1002/ccd.1810330115.
Quantitative coronary angiography (QCA) is a validated and widely accepted method to investigate changes in arterial dimension over time. Calibration of measurements is enabled by the use of the coronary catheter as a scaling device. The dimensions and laminar composition of coronary catheters, however, have changed significantly over recent years and the suitability of the current generation of coronary catheters for calibration purposes has not been validated. We therefore recorded 57 coronary guiding catheters on cinefilm, and compared their automated quantitative measurements (Cardiovascular Angiography Analysis System, CAAS) with their true values (precision micrometer). We found an overall underestimation of quantitatively derived dimensions, ranging from -8.9 to +4% for water-filled catheters and from -15.5 to -3.9% for contrast-filled catheters. In conclusion, while the current generation of coronary guiding catheters shows a wide variety in radiological quality, it can be clearly detected by the CAAS system, and is suitable for calibration of QCA measurements (with the exception of the DVI atherectomy catheter), provided that calibration is done on contrast-empty catheters.
定量冠状动脉造影术（QCA）是一种经过验证且被广泛接受的用于研究动脉尺寸随时间变化的方法。通过使用冠状动脉导管作为缩放装置来实现测量的校准。然而，近年来冠状动脉导管的尺寸和层流组成发生了显著变化，目前一代冠状动脉导管用于校准目的的适用性尚未得到验证。因此，我们在电影胶片上记录了57根冠状动脉引导导管，并将其自动定量测量值（心血管造影分析系统，CAAS）与其真实值（精密测微计）进行了比较。我们发现定量得出的尺寸总体上被低估，对于充满水的导管，低估范围为-8.9%至+4%，对于充满造影剂的导管，低估范围为-15.5%至-3.9%。总之，虽然目前一代冠状动脉引导导管在放射学质量上存在很大差异，但CAAS系统可以清楚地检测到，并且适用于QCA测量的校准（除DVI旋切导管外），前提是在校准造影剂排空的导管时进行校准。
