Del Genio A, Napolitano V, Allaria A, Amato G, Fei L, Albino V
Divisione di alta specializzazione chirurgica delle malattie dell'esofago e dell'apparato digerente, IIa Università di Napoli.
Chir Ital. 1994;46(3):5-10.
Thirty-two consecutive patients with esophageal carcinoma (squamous cell carcinoma: 23, adenocarcinoma: 9) were pre-operatively examined by endoscopic ultrasonography (EUS) in order to evaluate the accuracy of this diagnostic procedure in loco-regional staging. Six patients were not operated on, due to a poor general conditions or widespread tumor disease and were not included in this study. Results of EUS staging from the remaining patients were compared with intra-operative exploration and histopathological evaluation of resection specimens. Seven stenosing tumors were not traversable by echoendoscope. In such cases the lesion was visualized only in part by scanning the top of the stenosis. The overall EUS accuracy in T staging was 80.7% (75% in T2 stage, 90.9% in T3, 71.4% in T4). Three tumors were overstaged; two not traversable stenosing tumors were understaged. The overall accuracy in N staging was 73% (sensitivity 77.7%, specificity 62.5%). For celiac nodes EUS sensitivity was only 57.1%. Authors conclude that the presence of a not traversable stenosis is still a limit for EUS in diagnosing infiltration of adjacent structures as well as in detecting lymph node metastases.
连续32例食管癌患者(鳞状细胞癌23例,腺癌9例)接受了术前内镜超声检查(EUS),以评估该诊断方法在局部区域分期中的准确性。6例患者因全身状况差或肿瘤广泛转移未接受手术,未纳入本研究。将其余患者的EUS分期结果与术中探查及切除标本的组织病理学评估结果进行比较。7例狭窄性肿瘤的超声内镜无法通过。在这种情况下,仅通过扫描狭窄顶部部分观察到病变。EUS在T分期中的总体准确率为80.7%(T2期为75%,T3期为90.9%,T4期为71.4%)。3例肿瘤分期过高;2例无法通过的狭窄性肿瘤分期过低。N分期的总体准确率为73%(敏感性77.7%,特异性62.5%)。对于腹腔淋巴结,EUS敏感性仅为57.1%。作者得出结论,存在无法通过的狭窄仍然是EUS诊断相邻结构浸润以及检测淋巴结转移的限制因素。