Dittler H J, Bollschweiler E, Siewert J R
Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München.
Dtsch Med Wochenschr. 1991 Apr 12;116(15):561-6. doi: 10.1055/s-2008-1063649.
The value of endosonography (ES) for diagnosing the stage of oesophageal carcinoma was analysed in 180 patients with this form of cancer (161 men and 19 women; mean age 57 [41-73] years). The tumour stenosis could not be passed in 54 patients (30%). Primary resection of the tumour was possible in 97 patients (53.9%). It is in these latter cases that the results of endosonography and histological findings in the resected specimen were compared. The sensitivity of ES for the depth of infiltration of the primary tumour was 85%, while for involvement of regional lymph nodes it was 75%. In those cases in which ES could be applied only at the tumour stenosis but not beyond, the staging sensitivity was 72%. According to the ES findings, R0-resection should have been possible in 87 of 97 patients (89.7%), but on the basis of the histological findings in only 65 patients (67%). Nonetheless, ES is at present the most accurate method of judging resectability and thus of formulating a multimodal preoperative treatment concept.
对180例食管癌患者(161例男性,19例女性;平均年龄57[41 - 73]岁)分析了内镜超声检查(ES)在诊断食管癌分期中的价值。54例患者(30%)的肿瘤狭窄无法通过。97例患者(53.9%)可行肿瘤一期切除。正是在这些患者中,比较了内镜超声检查结果与切除标本的组织学检查结果。ES对原发肿瘤浸润深度的敏感性为85%,对区域淋巴结受累情况的敏感性为75%。在那些只能在肿瘤狭窄处应用ES而无法超出该范围的病例中,分期敏感性为72%。根据ES检查结果,97例患者中有87例(89.7%)应可行R0切除,但根据组织学检查结果,只有65例患者(67%)可行R0切除。尽管如此,目前ES仍是判断可切除性从而制定多模式术前治疗方案的最准确方法。