[Protein biosynthesis of the xenogeneic heart during perfusion with the aid of a donor].

Biosynthesis of sarcoplasmic and contractile proteins was studied in cat heart, extracorporeally connected to the rabbit circulation. Biosynthesis of sarcoplasmic proteins was inhibited by 34-40% in ventriculus dexter of the perfused xenogenic heart. Heteroperfusion caused an increased incorporation of 35S-methionine into total proteins of the right auricle and of the interventricular septa and also into contractile proteins of both myocardium ventricles of rabbit-donor. The heteroperfusion did not affect the penetration of the labelled amino acid into various parts of perfused and donor hearts.