Korotkina R N, Nikulin V I
Vopr Med Khim. 1976 Jul-Aug;22(4):465-9.
Biosynthesis of sarcoplasmic and contractile proteins was studied in cat heart, extracorporeally connected to the rabbit circulation. Biosynthesis of sarcoplasmic proteins was inhibited by 34-40% in ventriculus dexter of the perfused xenogenic heart. Heteroperfusion caused an increased incorporation of 35S-methionine into total proteins of the right auricle and of the interventricular septa and also into contractile proteins of both myocardium ventricles of rabbit-donor. The heteroperfusion did not affect the penetration of the labelled amino acid into various parts of perfused and donor hearts.
在与兔循环系统体外连接的猫心脏中，研究了肌浆蛋白和收缩蛋白的生物合成。在灌注的异种心脏右心室中，肌浆蛋白的生物合成受到34%-40%的抑制。异种灌注导致35S-甲硫氨酸掺入右心耳和室间隔的总蛋白中增加，也掺入兔供体两个心室心肌的收缩蛋白中。异种灌注不影响标记氨基酸进入灌注心脏和供体心脏各个部位。
