Srivastava L M, Vasisht S, Agarwal D P, Goedde H W
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi.
Alcohol Alcohol. 1994 Jan;29(1):11-24.
This paper reviews the much discussed association between alcohol intake, lipoproteins and coronary heart disease (CHD). Epidemiological studies have consistently shown an inverse trend between low to moderate alcohol consumption and CHD. Such a protective effect of alcohol against atherosclerosis has been associated with the elevated concentration of HDL-cholesterol induced by alcohol. However, the underlying mechanisms whereby alcohol drinking enhances HDL-cholesterol levels are not yet fully clear. Various lifestyle variables, namely diet, smoking, hypertension, body mass index and exercise, can affect the lipoprotein status in both users and non-users of alcohol.
本文综述了关于酒精摄入、脂蛋白与冠心病(CHD)之间备受讨论的关联。流行病学研究一致显示,低至适度饮酒与冠心病之间呈负相关趋势。酒精对动脉粥样硬化的这种保护作用与酒精诱导的高密度脂蛋白胆固醇(HDL-胆固醇)浓度升高有关。然而,饮酒提高HDL-胆固醇水平的潜在机制尚未完全明确。各种生活方式变量,即饮食、吸烟、高血压、体重指数和运动,均可影响饮酒者和不饮酒者的脂蛋白状况。