Shi X F, Du D J, Xie D C, Ran C Q
Sichuan Institute of Chinese Materia Medica, Chongqing.
Zhongguo Zhong Yao Za Zhi. 1993 Nov;18(11):687-90, 704.
Clerodendrum B(I) at dosage of 100g/kg ip or sc for 7 days was shown to have antitumor effect on hepatic carcinoma and sarcoma 180 in mice. In the mean time, 100g/kg sc of (I) interrupted 3H-TdR incorporation into DNA of sarcoma 180 cells in mice, 100, 10g/kg sc of (I) could suppress the phagocytic activity of the peritoneal macrophage against the CRBC (chicken red blood cells) in mice, 100g/kg sc of (I) also made the production of serum hemolysin less than one half of that of the control in mice immunized with SRBC. Clerodendrum C at 100g/kg could inhibit the growth of hepatic carcinoma in mice.
