Yeğen C, Aktan A O, Saraç A M, Yalin R
Marmara University Hospital, Department of General Surgery, Istanbul, Turkey.
Endocr Regul. 1993 Mar;27(1):23-5.
A 67 year old patient with overt signs of hyperthyroidism had high serum TSH values in addition to high T3 and T4 values. Initial treatment with propyltiouracil (PTU) reduced the high serum thyroid hormone levels but TSH levels were further increased. With an augmented TSH response to TRH and negative sella tomography, diagnosis of inappropriate secretion of TSH was made. PTU was stopped and bromocriptine 10 mg daily given with perfect result in 18 weeks. The patient is euthyroid on bromocriptine therapy.
一名67岁有明显甲状腺功能亢进体征的患者，除血清T3和T4值升高外，血清促甲状腺激素（TSH）值也很高。最初使用丙硫氧嘧啶（PTU）治疗降低了血清甲状腺激素的高值，但TSH水平进一步升高。由于对促甲状腺激素释放激素（TRH）的TSH反应增强且蝶鞍断层扫描阴性，诊断为TSH分泌不当。停用PTU，每天给予10毫克溴隐亭，18周后效果良好。患者接受溴隐亭治疗后甲状腺功能正常。
