Baliga M, Holmquist N D, Espinoza C G
Department of Pathology, Louisiana State University Medical Center, New Orleans.
Diagn Cytopathol. 1994;10(1):33-6. doi: 10.1002/dc.2840100109.
The extracranial spread of a primary intracranial tumor is an infrequent occurrence. The most common metastatic sites in order of frequency are bone, lymph nodes, and soft tissue. Analysis of the literature uncovered only two case reports of medulloblastoma that had metastasized to the breast. Both of these cases were diagnosed by open surgical biopsies. We present a case of medulloblastoma metastatic to the breast which was diagnosed by fine-needle aspiration biopsy. This diagnosis was subsequently confirmed by a tru-cut surgical biopsy and was further supported by immunohistochemical studies.
原发性颅内肿瘤的颅外扩散并不常见。按发生频率排序,最常见的转移部位是骨、淋巴结和软组织。文献分析仅发现两例髓母细胞瘤转移至乳腺的病例报告。这两例均通过开放性手术活检确诊。我们报告一例通过细针穿刺活检诊断为转移至乳腺的髓母细胞瘤病例。该诊断随后经粗针手术活检得以证实,并得到免疫组化研究的进一步支持。